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| US Open | ||
| Surface: Hard | Date: Aug. 26 - Sep. 8 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Maria Sharapova | Win | 6-1, 6-1 |
| Second Round | Catherine McNally | Win | 5-7, 6-3, 6-1 |
| Third Round | Karolina Muchova | Win | 6-3, 6-2 |
| Fourth Round | Petra Martic | Win | 6-3, 6-4 |
| Quarterfinals | Qiang Wang | Win | 6-1, 6-0 |
| Semifinals | Elina Svitolina | Win | 6-3, 6-1 |
| Final | Bianca Andreescu | Loss | 3-6, 5-7 |
| Rogers Cup presented by National Bank | ||
| Surface: Hard | Date: Aug. 5 - Aug. 11 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Elise Mertens | Win | 6-3, 6-3 |
| Third Round | Ekaterina Alexandrova | Win | 7-5, 6-4 |
| Quarterfinals | Naomi Osaka | Win | 6-3, 6-4 |
| Semifinals | Marie Bouzkova | Win | 1-6, 6-3, 6-3 |
| Final | Bianca Andreescu | Loss | 1-3 Retired |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 1 - Jul. 14 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Giulia Gatto-Monticone | Win | 6-2, 7-5 |
| Second Round | Kaja Juvan | Win | 2-6, 6-2, 6-4 |
| Third Round | Julia Goerges | Win | 6-3, 6-4 |
| Fourth Round | Carla Suarez Navarro | Win | 6-2, 6-2 |
| Quarterfinals | Alison Riske | Win | 6-4, 4-6, 6-3 |
| Semifinals | Barbora Strycova | Win | 6-1, 6-2 |
| Final | Simona Halep | Loss | 2-6, 2-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 26 - Jun. 9 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Vitalia Diatchenko | Win | 2-6, 6-1, 6-0 |
| Second Round | Kurumi Nara | Win | 6-3, 6-2 |
| Third Round | Sofia Kenin | Loss | 2-6, 5-7 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 12 - May 19 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Rebecca Peterson | Win | 6-4, 6-2 |
| Second Round | Venus Williams | Loss | Retired |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 19 - Mar. 31 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Rebecca Peterson | Win | 6-3, 1-6, 6-1 |
| Third Round | Qiang Wang | Loss | Retired |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 6 - Mar. 17 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Victoria Azarenka | Win | 7-5, 6-3 |
| Third Round | Garbine Muguruza | Loss | 3-6, 0-1 Retired |
| Australian Open | ||
| Surface: Hard | Date: Jan. 14 - Jan. 27 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Tatjana Maria | Win | 6-0, 6-2 |
| Second Round | Eugenie Bouchard | Win | 6-2, 6-2 |
| Third Round | Dayana Yastremska | Win | 6-2, 6-1 |
| Fourth Round | Simona Halep | Win | 6-1, 4-6, 6-4 |
| Quarterfinals | Karolina Pliskova | Loss | 4-6, 6-4, 5-7 |
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