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| French Open | ||
| Surface: Red Clay | Date: May 28 - Jun. 10 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Marta Kostyuk | Win | 6-3, 6-2 |
| Second Round | Iryna Shymanovich |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 9 - May 21 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Sofia Kenin | Loss | 6-7 (4-7), 2-6 |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 25 - May 6 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Sorana Cirstea | Win | 6-4, 6-3 |
| Third Round | Camila Osorio | Win | 6-4, 7-5 |
| Fourth Round | Mirra Andreeva | Win | 6-3, 6-1 |
| Quarterfinals | Mayar Sherif | Win | 2-6, 6-2, 6-1 |
| Semifinals | Maria Sakkari | Win | 6-4, 6-1 |
| Final | Iga Swiatek | Win | 6-3, 3-6, 6-3 |
| Porsche Tennis Grand Prix | ||
| Surface: Clay | Date: Apr. 17 - Apr. 23 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Barbora Krejcikova | Win | 6-2, 6-3 |
| Quarterfinals | Paula Badosa | Win | 4-6, 6-4, 6-4 |
| Semifinals | Anastasia Potapova | Win | 6-1, 6-2 |
| Final | Iga Swiatek | Loss | 3-6, 4-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 21 - Apr. 1 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Shelby Rogers | Win | 6-4, 6-3 |
| Third Round | Marie Bouzkova | Win | 6-1, 6-2 |
| Fourth Round | Barbora Krejcikova | Win | 6-3, 6-2 |
| Quarterfinals | Sorana Cirstea | Loss | 4-6, 4-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 8 - Mar. 19 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Evgeniya Rodina | Win | 6-2, 6-0 |
| Third Round | Lesia Tsurenko | Win | Retired |
| Fourth Round | Barbora Krejcikova | Win | 6-3, 2-6, 6-4 |
| Quarterfinals | Coco Gauff | Win | 6-4, 6-0 |
| Semifinals | Maria Sakkari | Win | 6-2, 6-3 |
| Final | Elena Rybakina | Loss | 6-7 (11-13), 4-6 |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 19 - Feb. 25 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Lauren Davis | Win | 6-0, 6-1 |
| Third Round | Jelena Ostapenko | Win | 2-6, 6-1, 6-1 |
| Quarterfinals | Barbora Krejcikova | Loss | 6-0, 6-7 (2-7), 1-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 28 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Tereza Martincova | Win | |
| Second Round | Shelby Rogers | Win | |
| Third Round | Elise Mertens | Win | |
| Fourth Round | Belinda Bencic | Win | |
| Quarterfinals | Donna Vekic | Win | |
| Semifinals | Magda Linette | Win | |
| Final | Elena Rybakina | Win |
| Adelaide International 1 | ||
| Surface: Hard | Date: Dec. 31 - Jan. 8 | Seed: 2 |
| Round | Opponent | W / L | Result |
| Second Round | Liudmila Samsonova | Win | |
| Quarterfinals | Marketa Vondrousova | Win | |
| Semifinals | Irina-Camelia Begu | Win | |
| Final | Linda Noskova | Win |
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