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| French Open | ||
| Surface: Red Clay | Date: May 28 - Jun. 10 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Cristina Bucsa | Win | 6-4, 6-0 |
| Second Round | Claire Liu | Win | 6-4, 6-0 |
| Third Round | Xinyu Wang | Win | 6-0, 6-0 |
| Fourth Round | Lesia Tsurenko |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 9 - May 21 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Anastasia Pavlyuchenkova | Win | 6-0, 6-0 |
| Third Round | Lesia Tsurenko | Win | 6-2, 6-0 |
| Fourth Round | Donna Vekic | Win | 6-3, 6-4 |
| Quarterfinals | Elena Rybakina | Loss | 6-2, 6-7 (3-7), 2-2 Retired |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 25 - May 6 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Julia Grabher | Win | 6-3, 6-2 |
| Third Round | Bernarda Pera | Win | 6-3, 6-2 |
| Fourth Round | Ekaterina Alexandrova | Win | 6-4, 6-7 (3-7), 6-3 |
| Quarterfinals | Petra Martic | Win | 6-0, 6-3 |
| Semifinals | Veronika Kudermetova | Win | 6-1, 6-1 |
| Final | Aryna Sabalenka | Loss | 3-6, 6-3, 3-6 |
| Porsche Tennis Grand Prix | ||
| Surface: Clay | Date: Apr. 17 - Apr. 23 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Qinwen Zheng | Win | 6-1, 6-4 |
| Quarterfinals | Karolina Pliskova | Win | 4-6, 6-1, 6-2 |
| Semifinals | Ons Jabeur | Win | 3-0 Retired |
| Final | Aryna Sabalenka | Win | 6-3, 6-4 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 8 - Mar. 19 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Claire Liu | Win | 6-0, 6-1 |
| Third Round | Bianca Andreescu | Win | 6-3, 7-6 (7-1) |
| Fourth Round | Emma Raducanu | Win | 6-3, 6-1 |
| Quarterfinals | Sorana Cirstea | Win | 6-2, 6-3 |
| Semifinals | Elena Rybakina | Loss | 2-6, 2-6 |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 19 - Feb. 25 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Leylah Fernandez | Win | 6-1, 6-1 |
| Third Round | Liudmila Samsonova | Win | 6-1, 6-0 |
| Semifinals | Coco Gauff | Win | 6-4, 6-2 |
| Final | Barbora Krejcikova | Loss | 4-6, 2-6 |
| Qatar Total Energies Open | ||
| Surface: Hard | Date: Feb. 13 - Feb. 18 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Danielle Collins | Win | 6-0, 6-1 |
| Quarterfinals | Belinda Bencic | Win | |
| Semifinals | Veronika Kudermetova | Win | 6-0, 6-1 |
| Final | Jessica Pegula | Win | 6-3, 6-0 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 28 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Jule Niemeier | Win | |
| Second Round | Camila Osorio | Win | |
| Third Round | Cristina Bucsa | Win | |
| Fourth Round | Elena Rybakina | Loss |
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